Caenorhabditis elegans functional genomics: Omic resonance
نویسندگان
چکیده
منابع مشابه
Caenorhabditis elegans functional genomics: omic resonance.
The nematode Caenorhabditis elegans is widely used as a model organism for studying many fundamental aspects of development and cell biology, including processes underlying human disease. The genome of C. elegans encodes over 19,000 protein-coding genes and hundreds of non-coding RNAs. The availability of whole genome sequence has facilitated the development of high throughput techniques for el...
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We have been working on functional genomics using C. elegans as a model organism. We first used cell-type specific markers and preexisting mutants to investigate how genotype-phenotype causal relationships are regulated. With the aid of transgenic methods, we analyzed various biological processes in C. elegans. We have developed efficient methods to isolate gene knockout strains. Thousands of s...
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ژورنال
عنوان ژورنال: Briefings in Functional Genomics and Proteomics
سال: 2004
ISSN: 1473-9550,1477-4062
DOI: 10.1093/bfgp/3.1.26